Microbial Isolates from Mammalian Hosts

In addition to the direct analysis of microbial ecosystems using molecular techniques, cultivation-based approaches are very important for microbiota research The isolation and characterization of strains make it possible to describe novel taxonomic and functional diversity, define the mechanisms underlying microbe- microbe and microbe- host interactions, and open avenues for biotechnological and clinical applications. Working with isolates generates a lot of technical, environmental, and biological data and metadata that must be taken care of according to the FAIR principles. Moreover, the use of isolates must adhere to the Nagoya Protocol. With NFDI4Microbiota, the University Hospital of RWTH Aachen and the Leibniz Institute DSMZ generate public collections of bacterial isolates from the intestine of human and animals to help the community. The naming of novel bacteria improves the resolution of microbiota analysis by high-throughput molecular methods, and researchers can use the isolates for their own experiments, enabling further progress in the field.

Human intestinal bacterial collection (HiBC):
www.hibc.rwth-aachen.de
Mouse intestinal bacterial collection (miBC):
www.dsmz.de/miBC
Chicken intestinal bacterial collection (ChiBAC):
www.dsmz.de/chibac

Credits

This section was written by Tom Clavel, ORCID (University Hospital RWTH Aachen, Germany).